Protein-Protein Interaction Investigated by Steered Molecular Dynamics: The TCR-pMHC Complex
نویسندگان
چکیده
منابع مشابه
Steered molecular dynamics investigations of protein function.
Molecular recognition and mechanical properties of proteins govern molecular processes in the cell that can cause disease and can be targeted for drug design. Single molecule measurement techniques have greatly advanced knowledge but cannot resolve enough detail to be interpreted in terms of protein structure. We seek to complement the observations through so-called Steered Molecular Dynamics (...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2008
ISSN: 0006-3495
DOI: 10.1529/biophysj.108.131383